![]() ![]() Symptoms of hyperthyroidism include weight loss, nervousness, rapid heartbeat, difficulty sleeping, frequent bowel movements and in women, less menstrual flow or loss of menstrual periods. Excessive TSH stimulates the thyroid gland to produce too much thyroid hormone (hyperthyroidism). TSH Secreting Tumor: This is the least common type of hormone producing pituitary tumor. Excessive cortisol production causes weight gain (particularly in the abdomen and neck), loss of muscle mass (legs, arms) and muscle weakness, depression, difficulty with concentration and memory, sleep disturbance, irritability, thinning of the skin with easy bruising, hypertension, diabetes mellitus, loss of bone mass (osteoporosis) with a risk for bone fractures and weakening of the immune system with a higher risk of developing infections. Harvey Cushing, a neurosurgeon, first described this condition in the 1920s and the pituitary condition is called Cushing’s disease. Other problems include joint pains (osteoarthritis), sleep apnea (excessive snoring, stopping breathing during sleep), hypertension (high blood pressure), diabetes mellitus (high blood sugar), colon polyps, change in teeth spacing, oily skin and acne.Ĭushing’s: The term “Cushing’s Disease” refers to the overproduction of cortisol by the adrenal glands caused by a pituitary tumor producing too much of the pituitary hormone, ACTH. Women who have gone through menopause do not have a change in menstrual periods to signal the problem in this situation, headache and loss of vision may be the first indicator of a prolactinoma.Īcromegaly: Enlargement of the hands, feet and face and excessive sweating are the most common features of excessive growth hormone production. In women of reproductive age a prolactin-producing tumor may cause milk in the breasts, a change in menstrual periods or loss of menses or problems becoming pregnant. Men may also have enlargement of the breasts, called gynecomastia. Prolactinoma: most commonly causes loss of sexual function and infertility in men. Specific types of tumors cause various symptoms and changes in body function. Diabetes insipidus is not high blood sugar levels it is a problem with the ability of the kidney to retain fluid because of a deficiency of the pituitary hormone, vasopressin (also called antidieuretic hormone) that regulates water balance. Occasionally a pituitary tumor causes diabetes insipidus, which results in frequent urination and excessive thirst. A tumor may interfere with normal pituitary function causing hypothyroidism (low thyroid hormone level), adrenal insufficiency (low cortisol level), hypogonadism (loss of sexual function and fertility in men, loss of menstrual periods or fertility problems in women). Headache may occur with a large or a small tumor. Headache may also occur the type of headache varies from patient to patient. A large tumor may cause loss of vision, particularly peripheral vision, if it compresses the optic chiasm (where the optic nerves come together, located above the pituitary gland). This depends on the type of tumor and the size of the tumor. UVA Child Development & Rehabilitation Center.Translational Health Research Institute of Virginia.Institute of Law, Psychiatry & Public Policy.Child Health Research Center (Pediatrics).Thaler Center for AIDS & Human Retrovirus Research Center for Immunity, Inflammation & Regenerative Medicine.Center for Behavioral Health & Technology.Molecular Physiology & Biological Physics.Microbiology, Immunology, & Cancer Biology (MIC).
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